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Muscular Dystrophy

Muscular dystrophy is a group of inherited diseases that progressively weaken the muscles that control movement. The nine major forms of muscular dystrophy include Myotonic, Duchenne, Becker Limb-girdle, Facioscapulohumeral, Congenital, Oculopharyngeal, Distal, Emery-Dreifuss. This disease can appear in infancy to middle-age and later. The severity is determined depending on what age the victim was diagnosed with Muscular Dystrophy. The various types of MD affect more than 50,000 Americans and an estimated 1 of every 5,600 to 7,700 males 5 through 24 years of age had some form of MD. But with recent advances in medical care, children with muscular dystrophy are living longer than ever before.

 

Genotype: X-linked recessive pattern

Phenotype: weakened muslces

Homozygous v. Heterozygous: homozygous

Dominant v. Recessive: recessive

Allele: D,M

Trait: weakened muscles,

Gene:  DMD

Punnett Square:

Pedigree:

Inheritance Pattern: X-Linked recessive

Polygenic inheritance:

Incomplete Dominance:

Codominance:

Multiple Alleles: D,M

Environmental Factors:

 

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